Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760182 | 0.89 | ADAM17 (0.48) | MMP1ADAM17HCRTR1HCRTR2KCNQ1 | |
| SCHEMBL5760549 | 0.87 | ALDH1A1 (0.47) | MMP1ADAM17ALDH1A1USP2LMNA | |
| SCHEMBL5760409 | 0.84 | MMP1 (0.48) | MMP1ADAM17 | |
| SCHEMBL8433497 | 0.82 | MMP1 (0.43) | MMP1ADAM17HCRTR1HCRTR2KCNQ1 | |
| SCHEMBL8433487 | 0.82 | MMP1 (0.43) | MMP1ADAM17HCRTR1HCRTR2KCNQ1 | |
| SCHEMBL5757157 | 0.80 | MMP1 (0.61) | MMP1ADAM17 | |
| SCHEMBL8573736 | 0.78 | ADAM17 (0.51) | MMP1ADAM17 | |
| SCHEMBL8573731 | 0.78 | ADAM17 (0.51) | MMP1ADAM17 | |
| SCHEMBL6380696 | 0.77 | MMP1 (0.59) | MMP1ADAM17 | |
| SCHEMBL6384644 | 0.76 | MMP1 (0.46) | MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-B1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PROD INC (US) | 2006-05-10 | — | — | EP | claimed |