Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 14/20 | 0.43 |
| ▸ | MMP13 | P45452 | 9/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433497 | 1.00 | MMP1 (0.43) | MMP1ADAM17MMP13HCRTR1HCRTR2 | |
| SCHEMBL5760182 | 0.89 | ADAM17 (0.48) | MMP1ADAM17MMP13HCRTR1HCRTR2 | |
| SCHEMBL8436802 | 0.88 | ADAM17 (0.49) | MMP1ADAM17MMP13 | |
| SCHEMBL5761276 | 0.82 | MMP1 (0.43) | MMP1ADAM17HCRTR1HCRTR2KCNQ1 | |
| SCHEMBL5757157 | 0.82 | MMP1 (0.61) | MMP1ADAM17 | |
| SCHEMBL6380696 | 0.80 | MMP1 (0.59) | MMP1ADAM17MMP13 | |
| SCHEMBL5760409 | 0.79 | MMP1 (0.48) | MMP1ADAM17 | |
| SCHEMBL8573731 | 0.79 | ADAM17 (0.51) | MMP1ADAM17MMP13 | |
| SCHEMBL8573736 | 0.79 | ADAM17 (0.51) | MMP1ADAM17MMP13 | |
| SCHEMBL6384644 | 0.78 | MMP1 (0.46) | MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |