Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766415 | 0.82 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL5767929 | 0.81 | KDM4E (0.42) | MAPK14 | |
| SCHEMBL4820991 | 0.79 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL5765833 | 0.77 | HSD11B1 (0.41) | MAPK14 | |
| SCHEMBL27108463 | 0.75 | MAPK14 (0.47) | MAPK14 | |
| SCHEMBL14306555 | 0.74 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL5766810 | 0.73 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL822105 | 0.72 | ACHE (0.52) | — | |
| SCHEMBL822299 | 0.69 | ACP3 (0.44) | — | |
| SCHEMBL477409 | 0.67 | ACP3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1601672-B1 | TRIAZOLO-PYRIDINES AS ANTI-INFLAMMATORY COMPOUNDS | PFIZER PROD INC (US) | 2006-07-26 | — | — | EP | disclosed |