Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307867 | 0.87 | ALDH1A1 (0.34) | LMNAALDH1A1TSHR | |
| SCHEMBL6059815 | 0.72 | — | — | |
| SCHEMBL16904971 | 0.72 | — | — | |
| SCHEMBL13327624 | 0.72 | — | — | |
| SCHEMBL11636685 | 0.69 | ALOX15 (0.34) | LMNAALDH1A1SMN1; SMN2MAPK1TP53 | |
| SCHEMBL2597029 | 0.69 | PTGS1 (0.54) | LMNATSHRUSP2MAPTCYP2C19 | |
| SCHEMBL2140315 | 0.69 | PTGS1 (0.54) | LMNATSHRUSP2MAPTCYP2C19 | |
| SCHEMBL2804462 | 0.68 | POLB (0.33) | — | |
| SCHEMBL19958880 | 0.68 | SMN1; SMN2 (0.37) | LMNAALDH1A1TSHRSMN1; SMN2USP2 | |
| SCHEMBL7992810 | 0.67 | LMNA (0.40) | LMNAALDH1A1TSHRSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611134-A1 | BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004092167-A1 | BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| US-5451642-A | Molding materials | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-19 | — | — | US | disclosed |
| US-5428091-A | Curable blends for molding, shaping; chemical resistance, mechanical properties | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0408255-B1 | Thermoplastic resin composition | SUMITOMO CHEMICAL CO (JP) | 1995-05-17 | — | — | EP | disclosed |
| EP-0485598-B1 | THERMOPLASTIC RESIN COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0391733-B1 | Thermoplastic resin composition | SUMITOMO CHEMICAL CO (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0394016-B1 | Resin composition | SUMITOMO CHEMICAL CO (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0382548-B1 | Thermoplastic resin composition | SUMITOMO CHEMICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5214049-A | Blend of polyphenylene ether, thermoplastic polyester and a hydroxycarboxylic acid or derivative; workability; solvent resistance; mechanical properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5116906-A | Molding materials | SUMITOMO CHEMICAL CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0485598-A1 | THERMOPLASTIC RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5112914-A | Blend of polyphenylene ether, thermoplastic polyester and amino resin | SUMITOMO CHEMICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-5070151-A | THERMOPLASTIC RESIN BLENDS OF POLYPHENYLENE ETHERS AND POLYLAC TAMS | SUMITOMO CHEMICAL CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0456259-A1 | Thermoplastic resin composition and article comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-13 | — | — | EP | disclosed |
| US-5019615-A | Polyphenylene ether/polyester blend with nitrodiamine compound | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0403056-A2 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-19 | — | — | EP | disclosed |
| EP-0394016-A2 | Resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0382548-A2 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-08-16 | — | — | EP | disclosed |
| EP-0368283-A2 | Resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |