1,3-Propanediol

1,3-Propanediol

SCHEMBL576409

CS(=O)(=O)O.CS(=O)(=O)O.OCCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of 1,3-Propanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CA2 P00918 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
ATR Q13535 1/20 0.37
LMNA P02545 3/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.33
CYP3A4 P08684 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
CA1 P00915 2/20 0.32
GRIA1 P42261 3/20 0.32
USP2 O75604 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Propanediol SCHEMBL7758303 1.00 ALDH1A1 (0.39) ALDH1A1CA2SMN1; SMN2ATRLMNA
1,4-Butanediol SCHEMBL15301979 0.93 SMN1; SMN2 (0.44) ALDH1A1CA2SMN1; SMN2ATRLMNA
1,4-Butanediol SCHEMBL130918 0.93 SMN1; SMN2 (0.44) ALDH1A1CA2SMN1; SMN2ATRLMNA
SCHEMBL4298844 0.90 LMNA (0.47) ALDH1A1CA2SMN1; SMN2ATRLMNA
1,6-Hexanediol SCHEMBL2180296 0.90 LMNA (0.47) ALDH1A1CA2SMN1; SMN2ATRLMNA
1,5-Pentanediol SCHEMBL2966670 0.90 LMNA (0.47) ALDH1A1CA2SMN1; SMN2ATRLMNA
SCHEMBL4300373 0.90 LMNA (0.47) ALDH1A1CA2SMN1; SMN2ATRLMNA
SCHEMBL28384587 0.90 LMNA (0.47) ALDH1A1CA2SMN1; SMN2ATRLMNA
1,3-Propanediol SCHEMBL2167722 0.88 ATR (0.32) ALDH1A1CA2SMN1; SMN2ATR
1,3-Propanediol SCHEMBL2167196 0.88 CAMK2A (0.39) ALDH1A1CA2SMN1; SMN2ATRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111154098-B Polyelectrolyte, preparation method and application thereof 湘潭大学 2022-07-05 CN claimed
CN-111154098-A Polyelectrolyte, preparation method and application thereof 湘潭大学 2020-05-15 CN claimed
US-7629085-B2 sulfur-containing acid ester and an alkyne-containing compound; excellent battery characteristics in cycle performance, electric capacity and storage property; e.g. 2-propynyl methyl carbonate and 1,3-propanesultone UBE INDUSTRIES, LTD. (JP) 2009-12-08 US claimed
US-12500268-B2 Nonaqueous electrolyte additive, nonaqueous electrolyte containing same, power storage device, and electric device AESC JAPAN LTD. (JP) 2025-12-16 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
EP-4273989-A1 SULFATE COMPOUND, NONAQUEOUS ELECTROLYTE CONTAINING SAME, AND POWER STORAGE DEVICE AESC Japan Ltd. (JP) 2023-11-08 EP disclosed
CN-116648804-A Sulfate compound, nonaqueous electrolyte containing same, and electricity storage device 远景动力技术(江苏)有限公司 2023-08-25 CN disclosed
US-20230253622-A1 NONAQUEOUS ELECTROLYTE ADDITIVE, NONAQUEOUS ELECTROLYTE CONTAINING SAME, POWER STORAGE DEVICE, AND ELECTRIC DEVICE ENVISION DYNAMICS TECHNOLOGY (JIANGSU) CO., LTD. (CN) 2023-08-10 US disclosed
CN-115911573-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-04-04 CN disclosed
US-11616253-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-03-28 US disclosed
CN-115668568-A Sulfate compound, nonaqueous electrolyte solution containing same, and electricity storage device 远景动力技术(江苏)有限公司 2023-01-31 CN disclosed
US-20070231707-A1 Nonaqueous Electrolytic Solution and Lithium Secondary Battery MU IONIC SOLUTIONS CORPORATION (JP) 2007-10-04 US disclosed
EP-1772924-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY Ube Industries, Ltd. (JP) 2007-04-11 EP disclosed
EP-1739783-A1 NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Ube Industries, Ltd. (JP) 2007-01-03 EP disclosed
US-20060166096-A1 Nonaqueous electrolyte secondary battery PANASONIC ENERGY CO., LTD (JP) 2006-07-27 US disclosed
EP-1095039-B1 NEW PHARMACEUTICALLY ACTIVE COMPOUNDS ASTRAZENECA AB (SE) 2003-08-27 EP disclosed
US-6436582-B1 A NON-AQUEOUS SOLVENT AND (II) AN ELECTROLYTE SALT DISSOLVED THEREIN AND (III) A DISULFONATE ESTER DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2002-08-20 US disclosed
US-6346625-B1 ENZYME INHIBITORS FOR PROTEIN KINASES ASTRAZENECA AB (SE) 2002-02-12 US disclosed
EP-1095039-A2 NEW PHARMACEUTICALLY ACTIVE COMPOUNDS AstraZeneca AB (SE) 2001-05-02 EP disclosed
WO-2000002877-A2 NEW PHARMACEUTICALLY ACTIVE COMPOUNDS ASTRAZENECA AB (SE) 2000-01-20 WO disclosed