Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 10/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764228 | 1.00 | XIAP (0.39) | XIAPTAAR1KDM1AALDH1A1MASP2 | |
| SCHEMBL5762000 | 1.00 | XIAP (0.39) | XIAPTAAR1KDM1AALDH1A1MASP2 | |
| SCHEMBL5762197 | 0.83 | XIAP (0.47) | XIAPALDH1A1 | |
| SCHEMBL5762909 | 0.83 | XIAP (0.47) | XIAPALDH1A1 | |
| SCHEMBL5764222 | 0.81 | KDM1A (0.52) | KDM1AMASP2GRIN2B | |
| SCHEMBL5763039 | 0.81 | MASP2 (0.42) | XIAPALDH1A1MASP2 | |
| SCHEMBL5761997 | 0.81 | KDM1A (0.52) | KDM1AMASP2GRIN2B | |
| SCHEMBL5761726 | 0.81 | MASP2 (0.42) | XIAPALDH1A1MASP2 | |
| SCHEMBL5764210 | 0.81 | KDM1A (0.52) | KDM1AMASP2GRIN2B | |
| SCHEMBL5763995 | 0.77 | NAAA (0.46) | XIAPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |