Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253009 | 0.81 | MEN1 (0.41) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL2563638 | 0.78 | MAPK9 (0.41) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL5264927 | 0.78 | HTT (0.35) | HTTRECQLGRM5 | |
| SCHEMBL6024760 | 0.78 | MAPK9 (0.34) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL6025036 | 0.78 | GAA (0.38) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL6443205 | 0.78 | MAPK9 (0.34) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL6024314 | 0.78 | MAPK9 (0.34) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL6443718 | 0.76 | GAA (0.39) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL1554049 | 0.76 | ALDH1A1 (0.42) | MAPK9MAPK10HTTKMT2ANPC1 | |
| SCHEMBL5753432 | 0.75 | PNMT (0.36) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546112-A4 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC INC (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1546112-A2 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | Biogen Idec MA Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004021989-A2 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2004-03-18 | — | — | WO | disclosed |