Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL6437917 | 0.84 | ALPI (0.45) | EPHX2TDP1ANPEPERAP2EPHX1 | |
| Cyclohexylamine SCHEMBL5767389 | 0.84 | ALPI (0.45) | EPHX2TDP1ANPEPERAP2EPHX1 | |
| Dl-Phenylalanine SCHEMBL9318540 | 0.82 | SLC7A5 (0.65) | EPHX2TDP1ANPEPERAP2EPHX1 | |
| Phenylalanine SCHEMBL9318542 | 0.82 | SLC7A5 (0.65) | EPHX2TDP1ANPEPERAP2EPHX1 | |
| SCHEMBL27571366 | 0.81 | NPC1 (0.50) | EPHX2TDP1ANPEPERAP2NPC1 | |
| SCHEMBL4826192 | 0.80 | CYP1A2 (0.61) | CPA1 | |
| SCHEMBL4316458 | 0.80 | CYP1A2 (0.61) | CPA1 | |
| SCHEMBL490844 | 0.80 | CYP1A2 (0.61) | CPA1 | |
| SCHEMBL6437914 | 0.79 | EPHX2 (0.48) | EPHX2TDP1ANPEPERAP2EPHX1 | |
| Bromide SCHEMBL1596942 | 0.79 | CYP1A2 (0.59) | CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487836-B1 | ETHANE-1,2-DIAMINO-BIS (2R)-2-BROMO-3-PHENYLPROPANOATE|, METHOD FOR PRODUCTION AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-09-06 | — | — | EP | disclosed |
| US-20050245764-A1 | Process for producing optically active 2-substituted carboxylic acid | KANEKA CORPORATION (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1487836-A1 | ETHANE-1,2-DIAMINO-BIS (2R)-2-BROMO-3-PHENYLPROPANOATE], METHOD FOR PRODUCTION AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2004-12-22 | — | — | EP | disclosed |
| EP-1422215-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUTED CARBOXYLIC ACID | KANEKA CORPORATION (JP) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003078434-A1 | ETHANE-1,2-DIAMINO-BIS[(2R)-2-BROMO-3-PHENYLPROPANOATE], METHOD FOR PRODUCTION AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245764-A1 | Process for producing optically active 2-substituted carboxylic acid | CA2, UACA, ATIC | EPHX2 485/4885TDP1 4766/4885ANPEP 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.