SCHEMBL576756

SCHEMBL576756

CC(C)c1cc(C2c3ccccc3-c3ccccc32)ccc1OCCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
LMNA P02545 2/20 0.40
IDO1 P14902 1/20 0.38
ADRB2 P07550 1/20 0.37
ALOX5AP P20292 2/20 0.37
FEN1 P39748 2/20 0.37
KDM4E B2RXH2 5/20 0.36
KMT2A Q03164 3/20 0.36
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8681933 0.89 KDM4E (0.37) ALDH1A1LMNAIDO1ADRB2ALOX5AP
SCHEMBL8686776 0.84 GLRA1 (0.36) ALDH1A1LMNAIDO1ADRB2ALOX5AP
SCHEMBL577512 0.83 L3MBTL1 (0.39) ALDH1A1LMNAIDO1ADRB2ALOX5AP
SCHEMBL576992 0.82 PPARG (0.40) ALDH1A1LMNAIDO1ADRB2ALOX5AP
SCHEMBL577449 0.81 TP53 (0.49) ALDH1A1LMNAADRB2ALOX5APFEN1
SCHEMBL576514 0.81 KDM4E (0.39) ALDH1A1IDO1ADRB2ALOX5APFEN1
SCHEMBL577661 0.80 KDM4E (0.40) ALDH1A1LMNAIDO1ADRB2ALOX5AP
SCHEMBL8681741 0.79 PPARG (0.39) ALDH1A1ADRB2ALOX5APFEN1KDM4E
SCHEMBL8682976 0.77 KDM4E (0.38) ALDH1A1LMNAALOX5APFEN1KDM4E
SCHEMBL8683806 0.76 TSHR (0.36) ALDH1A1ADRB2ALOX5APFEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272889-B1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2013-09-04 EP disclosed
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed
EP-2180014-B1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL CO (JP) 2011-12-14 EP disclosed
EP-2272889-A1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL Mitsubishi Gas Chemical Company, Inc. (JP) 2011-01-12 EP disclosed
EP-2180014-A1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-04-28 EP disclosed
US-5780194-A PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL MITA INDUSTRIAL CO., LTD. (JP) 1998-07-14 US disclosed