SCHEMBL577661

SCHEMBL577661

CC(C)(C)c1cc(C2c3ccccc3-c3ccccc32)ccc1OCCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 6/20 0.40
AR P10275 1/20 0.39
ALOX5AP P20292 2/20 0.36
FEN1 P39748 2/20 0.36
MAPK1 P28482 3/20 0.35
RARA P10276 2/20 0.35
RARB P10826 2/20 0.35
RARG P13631 2/20 0.35
TP53 P04637 1/20 0.35
RAB9A P51151 1/20 0.35
IDO1 P14902 1/20 0.35
GAA P10253 2/20 0.35
LMNA P02545 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 2/20 0.34
HTR7 P34969 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577512 0.83 L3MBTL1 (0.39) KDM4EALDH1A1ARALOX5APFEN1
SCHEMBL577449 0.81 TP53 (0.49) KDM4EALDH1A1ALOX5APFEN1MAPK1
SCHEMBL577074 0.81 AR (0.38) KDM4EALDH1A1ARALOX5APFEN1
SCHEMBL576514 0.81 KDM4E (0.39) KDM4EALDH1A1ALOX5APFEN1MAPK1
SCHEMBL576756 0.80 ALDH1A1 (0.40) KDM4EALDH1A1ARALOX5APFEN1
SCHEMBL8681741 0.79 PPARG (0.39) KDM4EALDH1A1ALOX5APFEN1MAPK1
SCHEMBL576992 0.78 PPARG (0.40) KDM4EALDH1A1ARALOX5APFEN1
SCHEMBL8681933 0.77 KDM4E (0.37) KDM4EALDH1A1ARALOX5APFEN1
SCHEMBL8682976 0.77 KDM4E (0.38) KDM4EALDH1A1ALOX5APFEN1MAPK1
SCHEMBL8686874 0.76 HPGD (0.42) KDM4EALOX5APFEN1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895663-B2 Polycarbonate resin composition and molded article thereof MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-25 US disclosed
US-20140031494-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2014-01-30 US disclosed
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed
EP-2180014-B1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL CO (JP) 2011-12-14 EP disclosed
US-8058384-B2 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-11-15 US disclosed
US-20100144995-A1 METHOD FOR PRODUCING THERMOPLASTIC RESIN, POLYESTER RESIN AND POLYCARBONATE RESIN, AND THEIR APPLICATIONS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-06-10 US disclosed
EP-2180014-A1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-04-28 EP disclosed