Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576514 | 0.86 | KDM4E (0.39) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL8682932 | 0.85 | ALOX5AP (0.32) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL8681741 | 0.84 | PPARG (0.39) | PPARGPPARDPPARAADRB2ALOX5AP | |
| SCHEMBL576756 | 0.82 | ALDH1A1 (0.40) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL8682976 | 0.82 | KDM4E (0.38) | PPARGALOX5APFEN1TP53MAPK1 | |
| SCHEMBL8686874 | 0.81 | HPGD (0.42) | ALOX5APFEN1TP53MAPK1RAB9A | |
| SCHEMBL577512 | 0.81 | L3MBTL1 (0.39) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL8681933 | 0.80 | KDM4E (0.37) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL577449 | 0.79 | TP53 (0.49) | ADRB2ALOX5APFEN1TP53MAPK1 | |
| SCHEMBL577661 | 0.78 | KDM4E (0.40) | ADRB2ALOX5APFEN1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418253-A1 | POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS | Mitsubishi Gas Chemical Company, Inc. (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-5780194-A | PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |