Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5767569

O=C(O)C(F)(F)F.O=C(O)CCCc1cscn1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.35
SLC6A3 Q01959 3/20 0.35
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HDAC3 O15379 1/20 0.35
ADRA1A P35348 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
PKM P14618 1/20 0.34
GPR142 Q7Z601 1/20 0.34
SCD O00767 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5818912 0.91 SMN1; SMN2 (0.41) SMN1; SMN2SLC6A3MAPK1KDM4EHDAC3
SCHEMBL7775035 0.85 TBXAS1 (0.42) KDM4EKDM4CSCDTBXAS1
SCHEMBL7186166 0.84 TBXAS1 (0.45) SCDTBXAS1
SCHEMBL16116690 0.84 TBXAS1 (0.45) SCDTBXAS1
SCHEMBL907879 0.84 KDM4E (0.44) SLC6A3MAPK1KDM4EHDAC6KDM4C
Citric Acid SCHEMBL4779312 0.76 ALDH1A1 (0.40) KDM4EPKMCYP1A2
SCHEMBL19051554 0.74 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EHDAC3HDAC4HDAC1
Oxalic Acid SCHEMBL27277082 0.71 KDM4E (0.39) SMN1; SMN2SLC6A3MAPK1KDM4EKDM4C
SCHEMBL21603086 0.68 PKM (0.40) SMN1; SMN2SLC6A3MAPK1KDM4EKDM4C
Trifluoroacetic Acid SCHEMBL30101402 0.68 KDM4E (0.74) SMN1; SMN2KDM4EKDM4CALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732893-A2 ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST Pfizer Japan, Inc. (JP) 2006-12-20 EP disclosed
WO-2005092858-A2 ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST PFIZER JAPAN INC. (JP) 2005-10-06 WO disclosed