Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL21061182 | 0.84 | SLC7A5 (0.42) | SLC7A5IRAK4FEN1 | |
| SCHEMBL522950 | 0.83 | TSHR (0.37) | IRAK4 | |
| SCHEMBL21587611 | 0.83 | TSHR (0.37) | IRAK4 | |
| SCHEMBL268203 | 0.83 | TSHR (0.37) | IRAK4 | |
| SCHEMBL6923351 | 0.73 | TSHR (0.35) | IRAK4 | |
| SCHEMBL3117336 | 0.70 | TSHR (0.33) | IRAK4 | |
| SCHEMBL8319395 | 0.70 | SMN1; SMN2 (0.34) | IRAK4 | |
| SCHEMBL523099 | 0.70 | SMN1; SMN2 (0.34) | IRAK4 | |
| SCHEMBL23718975 | 0.70 | IRAK4 (0.33) | IRAK4FEN1 | |
| SCHEMBL3123114 | 0.68 | PDE4A (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212072-B2 | Process for the preparation of pregabalin | Divi's Laboratories, Ltd. (IN) | 2012-07-03 | — | — | US | disclosed |
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | DIVI'S LABORATORIES LIMITED (IN) | 2012-02-16 | — | — | US | disclosed |
| EP-2418194-A1 | Process for the preparation of pregabalin | Divi's Laboratories Limited (IN) | 2012-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | GABRA5, GABRA6, GABRE | SLC7A5 1136/4885MME 2975/4885IRAK4 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.