Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773773 | 0.86 | FFAR4 (0.43) | FFAR4GABRA5CCNCCDK8MIF | |
| SCHEMBL5772554 | 0.86 | FFAR4 (0.46) | FFAR4IDO1 | |
| SCHEMBL5771218 | 0.84 | FFAR4 (0.41) | FFAR4GABRA5CCNCCDK8MIF | |
| SCHEMBL5776310 | 0.81 | FFAR4 (0.55) | FFAR4GABRA5 | |
| SCHEMBL5772569 | 0.80 | MAPT (0.46) | FFAR4GABRA5CCNCCDK8 | |
| SCHEMBL5776250 | 0.78 | CA2 (0.35) | IDO1GABRA5 | |
| SCHEMBL5775809 | 0.78 | PARP1 (0.36) | IDO1GABRA5MAPK1 | |
| SCHEMBL5775587 | 0.77 | CCNC (0.41) | IDO1CCNCCDK8MIFMAPK1 | |
| SCHEMBL5769963 | 0.72 | MEN1 (0.41) | IDO1 | |
| SCHEMBL23497373 | 0.72 | PTPN1 (0.45) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | MOMOSE YU | 2006-04-20 | — | — | US | disclosed |
| US-7022725-B2 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040048908-A1 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1340749-A1 | ISOXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | INSR, GPR119, INSRR | FFAR4 143/4885IDO1 1275/4885GABRA5 707/4885 |
| US-20040048908-A1 | Isoxazole derivatives | GPR119, INSR, IRS1 | FFAR4 145/4885IDO1 693/4885GABRA5 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.