Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 5/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767550 | 0.76 | MAPK14 (0.38) | — | |
| SCHEMBL5773725 | 0.72 | MAPK14 (0.42) | MAPTALDH1A1 | |
| SCHEMBL5774512 | 0.71 | ALDH1A1 (0.40) | KMT2ALMNAMAPTNPSR1PDE5A | |
| SCHEMBL5770827 | 0.71 | TP53 (0.48) | KMT2ALMNAMAPTHTTNPSR1 | |
| SCHEMBL8293200 | 0.69 | SSTR5 (0.53) | SSTR5KMT2ALMNAMAPTHTT | |
| SCHEMBL5773665 | 0.68 | PI4KB (0.54) | — | |
| SCHEMBL18058953 | 0.65 | THRB (0.50) | KMT2ALMNAMAPTHTTNPSR1 | |
| SCHEMBL6335815 | 0.65 | HTT (0.67) | ACHEBCHEKMT2AMAPTHTT | |
| SCHEMBL4227761 | 0.64 | ACHE (0.57) | ACHEBCHEHTTSMN1; SMN2 | |
| SCHEMBL13319055 | 0.63 | SSTR5 (0.68) | SSTR5KMT2ALMNAMAPTNTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554272-B1 | BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE | LILLY CO ELI (US) | 2006-10-25 | — | — | EP | disclosed |