SCHEMBL5771616

SCHEMBL5771616

CC(C)Oc1cc(CO)c(F)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.41
PPOX P50336 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
RORC P51449 1/20 0.38
S1PR1 P21453 2/20 0.37
KDM4E B2RXH2 1/20 0.36
KMO O15229 3/20 0.35
KCNQ3 O43525 1/20 0.35
KCNQ2 O43526 1/20 0.35
GAA P10253 2/20 0.35
MAPK1 P28482 1/20 0.34
MAP2 P11137 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5773826 0.85 CSNK2A1 (0.42) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL7942796 0.85 CSNK2A1 (0.42) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL5775031 0.81 KMO (0.43) CSNK2A1PPOXRORCS1PR1KMO
SCHEMBL6739489 0.81 TAAR1 (0.51) PPOXGAA
SCHEMBL5773291 0.80 CSNK2A1 (0.39) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL7942213 0.77 PPOX (0.43) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL16727184 0.75 PPOX (0.43) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL19088281 0.74 CSNK2A1 (0.44) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL4678114 0.74 PPOX (0.45) CSNK2A1PPOXMEN1KMT2ALMNA
SCHEMBL7480745 0.74 PPOX (0.42) CSNK2A1PPOXMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885885-B1 PYRIDONE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2006-01-04 EP disclosed
US-6472348-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2002-10-29 US disclosed
US-6265349-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2001-07-24 US disclosed
US-6242634-B1 OF HERBICIDES, HALOPHENYL COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-05 US disclosed
US-6100257-A 2-HALOALKYL,3-(HALOALKYL, ALKENYL, OR ALKYNYL),5-(SUBSTITUTED PHENYL OR HETEROCYCLE),6-ALKYL-PYRIMIDIN-4-ONE COMPOUNDS OF GIVEN STRUCTURE; USE AS HERBICIDES SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-08-08 US disclosed
US-6048823-A Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-11 US disclosed
EP-0885885-A1 PYRIDONE DERIVATIVES AND HERBICIDES KumaiI Chemical Industry Co., Ltd. (JP) 1998-12-23 EP disclosed
EP-0850229-A1 PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-07-01 EP disclosed
WO-1997006150-A1 PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-20 WO disclosed