SCHEMBL5773826

SCHEMBL5773826

CC(C)Oc1cc(CBr)c(F)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.42
PPOX P50336 3/20 0.40
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
RORC P51449 1/20 0.36
GAA P10253 2/20 0.35
KDM4E B2RXH2 2/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KMO O15229 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
MAP2 P11137 1/20 0.33
MAPK1 P28482 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7942796 0.86 CSNK2A1 (0.42) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL5771616 0.85 CSNK2A1 (0.41) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL5773291 0.84 CSNK2A1 (0.39) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL6738129 0.82 TAAR1 (0.51) PPOXMEN1LMNAKMT2AGAA
SCHEMBL5775031 0.80 KMO (0.43) CSNK2A1PPOXRORCGAAKMO
SCHEMBL7480745 0.79 PPOX (0.42) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL16727184 0.77 PPOX (0.43) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL19088281 0.76 CSNK2A1 (0.44) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL8919751 0.75 RORC (0.40) CSNK2A1PPOXMEN1LMNAKMT2A
SCHEMBL7942213 0.75 PPOX (0.43) CSNK2A1PPOXMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885885-B1 PYRIDONE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2006-01-04 EP disclosed
US-6472348-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2002-10-29 US disclosed
US-6265349-B1 Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2001-07-24 US disclosed
US-6048823-A Pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-11 US disclosed
EP-0885885-A1 PYRIDONE DERIVATIVES AND HERBICIDES KumaiI Chemical Industry Co., Ltd. (JP) 1998-12-23 EP disclosed