Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | PPOX | P50336 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942213 | 0.83 | PPOX (0.43) | KMOP2RX3RORCPPOXCSNK2A1 | |
| SCHEMBL5771616 | 0.81 | CSNK2A1 (0.41) | KMORORCS1PR1PPOXCSNK2A1 | |
| SCHEMBL5773826 | 0.80 | CSNK2A1 (0.42) | KMORORCS1PR1PPOXCSNK2A1 | |
| SCHEMBL7942796 | 0.80 | CSNK2A1 (0.42) | KMORORCS1PR1PPOXCSNK2A1 | |
| SCHEMBL7489023 | 0.77 | ALDH1A1 (0.44) | KMOP2RX3RORCS1PR1PPOX | |
| SCHEMBL927651 | 0.76 | AKR1B1 (0.44) | CHRM1CXCL8 | |
| SCHEMBL7482306 | 0.75 | RORC (0.48) | KMORORCPPOXCSNK2A1GAA | |
| SCHEMBL5773291 | 0.75 | CSNK2A1 (0.39) | P2RX3RORCPPOXCSNK2A1GAA | |
| SCHEMBL5746010 | 0.74 | HSD17B10 (0.47) | PTGDR | |
| SCHEMBL5772458 | 0.73 | PPOX (0.36) | P2RX3RORCPPOXCSNK2A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885885-B1 | PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |