Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 15/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381665 | 0.90 | P2RX3 (0.35) | DPP4 | |
| SCHEMBL2965812 | 0.87 | POLB (0.42) | POLBGAANPSR1DPP4DPP9 | |
| SCHEMBL13866880 | 0.83 | POLB (0.31) | TRPA1POLBGAANPSR1 | |
| SCHEMBL5771868 | 0.78 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL5719040 | 0.77 | DPP4 (0.42) | DPP4DPP9 | |
| SCHEMBL23146029 | 0.75 | KMT2A (0.41) | POLBGAANPSR1CYP1A2CYP2C19 | |
| SCHEMBL6422754 | 0.75 | DPP4 (0.44) | DPP4DPP9 | |
| SCHEMBL5790131 | 0.73 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL2957435 | 0.72 | PDE4A (0.48) | TRPA1 | |
| SCHEMBL3879335 | 0.72 | NR1H2 (0.34) | POLBNPSR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | TRPA1 3743/4885POLB 4529/4885GAA 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.