Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419570 | 1.00 | TRPA1 (0.41) | TRPA1NPC1RAB9AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3826140 | 0.98 | TRPA1 (0.39) | TRPA1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11443029 | 0.75 | TRPA1 (0.36) | TRPA1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11443028 | 0.75 | TRPA1 (0.36) | TRPA1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10716002 | 0.70 | TRPA1 (0.38) | TRPA1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2104835 | 0.67 | TRPA1 (0.41) | TRPA1NOS3NOS1NOS2 | |
| SCHEMBL29444405 | 0.67 | HTR5A (0.32) | KDM4E | |
| SCHEMBL1072976 | 0.67 | — | — | |
| SCHEMBL11035108 | 0.66 | TRPA1 (0.58) | TRPA1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3707141 | 0.65 | NOS3 (0.39) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164531-A | 2, 4-disubstituted 4H-benzo [ d ] [1,3] oxazine series, preparation method and application thereof | 江西师范大学 | 2023-12-05 | — | — | CN | claimed |
| CN-114671825-B | Synthesis method of chiral 4H-3, 1-benzoxazine compound containing selenoaryl | 安徽泽升科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115850200-A | Polymerizable 3, 1-benzoxazine substituted phenol monomer, preparation method, cured product and application | 西安交通大学 | 2023-03-28 | — | — | CN | claimed |
| CN-111943903-B | Preparation method of 3, 1-benzoxazine derivative started by ketone free radical | 宁波大学 | 2022-10-04 | — | — | CN | claimed |
| CN-114671825-A | Synthetic method of chiral 4H-3, 1-benzoxazine compound containing selenium aryl | 安徽泽升科技有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-110804740-B | Method for electrochemically synthesizing sulfonyl-containing 4-hydro-benzo [ d ] [1,3] oxazine and derivative thereof | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-111943903-A | Preparation method of 3, 1-benzoxazine derivative started by ketone free radical | 宁波大学 | 2020-11-17 | — | — | CN | claimed |
| CN-110804740-A | Method for electrochemically synthesizing sulfonyl-containing 4-hydro-benzo [ d ] [1,3] oxazine and derivative thereof | 华南理工大学 | 2020-02-18 | — | — | CN | claimed |
| CN-106831632-B | A kind of 4H-3,1- benzoxazine compounds catalysis oxidation synthetic method | 浙江工业大学 | 2019-04-23 | — | — | CN | claimed |
| US-RE47009-E1 | HDAC inhibitors and therapeutic methods using the same | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2018-08-28 | — | — | US | claimed |
| US-RE32087-E | 4H-3,1-Benzoxazine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-25 | — | — | US | claimed |
| US-4523942-A | 4H-3,1-Benzoxazine derivatives, compositions and herbicidal use | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-18 | — | — | US | claimed |
| EP-0049398-B1 | 4H-3,1-BENZOXAZIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-06 | — | — | EP | claimed |
| EP-0120480-A1 | 4H-3,1-benzoxazine derivatives, process for producing the same and agricultural or horticultural fungicide containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-10-03 | — | — | EP | claimed |
| EP-0017931-B1 | 4H-3,1-BENZOXAZINE DERIVATIVES, METHODS OF THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRABLE VEGETATION | BASF Aktiengesellschaft (DE) | 1984-03-07 | — | — | EP | claimed |
| EP-0032242-B1 | 4H-3,1-BENZOXAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN INHIBITING THE GROWTH OF UNWANTED PLANTS | BASF Aktiengesellschaft (DE) | 1983-12-14 | — | — | EP | claimed |
| US-4363651-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | claimed |
| US-4315766-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4261894-A | Process for the preparation of optionally substituted 2,3-indolinediones | SANDOZ, INC. (US) | 1981-04-14 | — | — | US | claimed |
| US-4212804-A | Process for the preparation of optionally substituted 2,3-indolinediones | SANDOZ, INC. (US) | 1980-07-15 | — | — | US | claimed |