Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797214 | 0.86 | MEN1 (0.51) | — | |
| SCHEMBL7506148 | 0.81 | MEN1 (0.46) | — | |
| SCHEMBL27554209 | 0.80 | MMP8 (0.50) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL7189265 | 0.79 | MMP8 (0.49) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL9435341 | 0.76 | MMP8 (0.62) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL28474562 | 0.75 | MMP8 (0.73) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL7052592 | 0.75 | MEN1 (0.48) | — | |
| SCHEMBL15944495 | 0.74 | MMP8 (0.77) | MMP8CA12CA1CA2CA9 | |
| Ethyl Acetate SCHEMBL8909263 | 0.74 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL266419 | 0.73 | MMP8 (0.74) | MMP8CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203767-B1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER LAMBERT CO (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1203767-A1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5441975-A | Anticholesterol agent | WARNER-LAMBERT COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5366987-A | Enzyme inhibitors, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1994019330-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-09-01 | — | — | WO | disclosed |