Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16589148 | 0.86 | — | — | |
| SCHEMBL5972840 | 0.86 | — | — | |
| SCHEMBL5799250 | 0.83 | KMT2A (0.58) | — | |
| SCHEMBL28188485 | 0.77 | NLRP3 (0.81) | NLRP3 | |
| SCHEMBL15944495 | 0.77 | MMP8 (0.77) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL266419 | 0.76 | MMP8 (0.74) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL5772297 | 0.76 | MMP8 (0.58) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL9679386 | 0.75 | KMT2A (0.55) | — | |
| SCHEMBL9679376 | 0.75 | KMT2A (0.55) | — | |
| SCHEMBL1044283 | 0.75 | NLRP3 (0.50) | MMP8NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994019330-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-09-01 | — | — | WO | disclosed |