SCHEMBL57723

SCHEMBL57723

c1ccc2c(c1)COCN2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GAA P10253 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
AHR P35869 1/20 0.34
PDK2 Q15119 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HSP90AA1 P07900 1/20 0.34
THRB P10828 1/20 0.34
HK1 P19367 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
HKDC1 Q2TB90 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4502710 0.78 ALOX15 (0.41) ALOX15HSD17B10GAANPSR1MEN1
SCHEMBL3003659 0.78 ALOX15 (0.41) ALOX15HSD17B10GAANPSR1MEN1
SCHEMBL24953238 0.78 GAA (0.38) ALOX15HSD17B10GAANPSR1MEN1
SCHEMBL11442903 0.75 ALOX15 (0.42) ALOX15HSD17B10GAANPSR1MEN1
SCHEMBL15360012 0.72 CHRNB2 (0.38) GAAMAPT
SCHEMBL29412510 0.71 CA12 (0.57) NPSR1MAPTRAB9AALDH1A1MAOA
SCHEMBL30345255 0.71 HTR5A (0.38) HSD17B10GAANPC1MAPTKDM4E
SCHEMBL26168163 0.71 CA12 (0.57) NPSR1MAPTRAB9AALDH1A1MAOA
SCHEMBL23571603 0.71 ALDH1A1 (0.41) HSD17B10GAAMAPTKDM4EHTR5A
SCHEMBL17430748 0.71 HTR5A (0.38) HSD17B10GAANPC1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
US-20240182460-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION 2024-06-06 US claimed
CN-115850200-B Polymerizable 3, 1-benzoxazine substituted phenol monomer, preparation method, cured product and application 西安交通大学 2024-05-14 CN claimed
WO-2024097172-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION (US) 2024-05-10 WO claimed
CN-115850200-A Polymerizable 3, 1-benzoxazine substituted phenol monomer, preparation method, cured product and application 西安交通大学 2023-03-28 CN claimed
CN-110204506-B CO 2 Synthesis of 1,4-dihydro-2H-3,1-benzoxazine-2-one derivative as C1 source 常州大学 2022-10-28 CN claimed
EP-2928888-A1 SUBSTITUTED PYRIDOPYRAZINES AS SYK INHIBITORS Hutchison Medipharma Limited (CN) 2015-10-14 EP claimed
WO-2014086316-A1 SUBSTITUTED PYRIDOPYRAZINES AS SYK INHIBITORS HUTCHISON MEDIPHARMA LIMITED (CN) 2014-06-12 WO claimed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP claimed
US-7674502-B2 bright gold, fluxing agents such as organometallics FERRO GMBH (DE) 2010-03-09 US claimed
US-20070243336-A1 Uv-Radiation-Curable Precious-Metal Preparation, Transfer Pictures Containing Said Preparation, and Process for Decoration Heraeus Deutschland GmbH & Co. KG (DE) 2007-10-18 US claimed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US claimed
US-20060134554-A1 Radiationhardenable printing media, transfer pictures produced therewith, and method for producing ceramic decorations FERRO GMBH (DE) 2006-06-22 US claimed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US claimed
CN-1753957-A Radiation-curable printing medium, transfer article made therefrom and method for making ceramic decorations FERRO GMBH (DE) 2006-03-29 CN claimed
EP-1597326-A1 RADIOHARDENABLE PRINTING MEDIA, TRANSFER PICTURES PRODUCED THEREWITH, AND METHOD FOR PRODUCING CERAMIC DECORATIONS Ferro GmbH (DE) 2005-11-23 EP claimed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP claimed
WO-2004076569-A1 RADIOHARDENABLE PRINTING MEDIA, TRANSFER PICTURES PRODUCED THEREWITH, AND METHOD FOR PRODUCING CERAMIC DECORATIONS FERRO GMBH (DE) 2004-09-10 WO claimed
US-5300497-A Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria TOYAMA CHEMICAL CO., LTD. (JP) 1994-04-05 US claimed
US-5185330-A Penicillins/ad/ TOYAMA CHEMICAL CO., LTD. (JP) 1993-02-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 ALOX15 2847/4885HSD17B10 467/4885GAA 4165/4885
US-20240182460-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 ALOX15 2996/4885HSD17B10 466/4885GAA 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.