Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964029 | 0.86 | KMT2A (0.37) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL5771257 | 0.81 | ELANE (0.32) | NPSR1POLBGAAALDH1A1ELANE | |
| SCHEMBL5719350 | 0.79 | ADORA2B (0.43) | KMT2AADORA2BNPSR1POLBALDH1A1 | |
| SCHEMBL2955104 | 0.79 | P2RX7 (0.43) | PDE4APDE4BPDE4CPDE4DADORA2B | |
| SCHEMBL5791762 | 0.78 | KMT2A (0.37) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL23146012 | 0.78 | KMT2A (0.43) | KMT2AADORA2BNPSR1POLBGAA | |
| SCHEMBL2957710 | 0.76 | ALDH1A1 (0.57) | KMT2AADORA2BPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL23146226 | 0.75 | KMT2A (0.35) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL5791764 | 0.74 | ALDH1A1 (0.34) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL6383869 | 0.73 | P2RX3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | PDE4A 39/4885PDE4B 38/4885PDE4C 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.