Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 10/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778323 | 0.89 | SLC2A1 (0.49) | SLC2A1KCNH2CCNT1CDK9 | |
| SCHEMBL5778145 | 0.89 | SLC2A1 (0.47) | SLC2A1KCNH2CCNT1CDK9SIGMAR1 | |
| SCHEMBL5775479 | 0.87 | SLC2A1 (0.48) | SLC2A1KCNH2CCNT1CDK9SIGMAR1 | |
| SCHEMBL5778699 | 0.86 | SLC2A1 (0.58) | SLC2A1KCNH2DRD2SIGMAR1MEN1 | |
| SCHEMBL5774194 | 0.86 | SLC2A1 (0.49) | SLC2A1KCNH2CCNT1CDK9SIGMAR1 | |
| SCHEMBL4268797 | 0.84 | SLC2A1 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL5772116 | 0.84 | SLC2A1 (0.48) | SLC2A1KCNH2DRD2SIGMAR1MEN1 | |
| SCHEMBL5773652 | 0.83 | SLC2A1 (0.47) | SLC2A1KCNH2DRD4DRD2SIGMAR1 | |
| SCHEMBL5775396 | 0.83 | KCNH2 (0.49) | SLC2A1KCNH2DRD2SIGMAR1 | |
| SCHEMBL5777366 | 0.83 | LMNA (0.47) | SLC2A1KCNH2DRD4DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |