Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774216 | 0.91 | SLC2A1 (0.49) | SLC2A1KCNH2SIGMAR1HTR1AADRA1D | |
| SCHEMBL5775396 | 0.86 | KCNH2 (0.49) | SLC2A1KCNH2SIGMAR1HTR1ADRD2 | |
| SCHEMBL5777366 | 0.84 | LMNA (0.47) | SLC2A1KCNH2SIGMAR1LMNAKMT2A | |
| SCHEMBL5772802 | 0.84 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1MEN1KMT2A | |
| SCHEMBL5773652 | 0.84 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1MAPTDRD2 | |
| SCHEMBL27579662 | 0.84 | KCNH2 (0.65) | SLC2A1KCNH2MCHR1 | |
| SCHEMBL4272906 | 0.84 | KCNH2 (0.65) | SLC2A1KCNH2MCHR1 | |
| SCHEMBL5255719 | 0.83 | SLC2A1 (0.43) | SLC2A1KCNH2 | |
| SCHEMBL5778699 | 0.83 | SLC2A1 (0.58) | SLC2A1KCNH2SIGMAR1LMNAMAPT | |
| SCHEMBL5777778 | 0.83 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |