Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 10/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773652 | 0.84 | SLC2A1 (0.47) | RAB9ASLC2A1KCNH2DRD2SIGMAR1 | |
| SCHEMBL4278930 | 0.84 | KCNH2 (0.63) | LMNAKMT2ASLC2A1KCNH2 | |
| SCHEMBL5772116 | 0.84 | SLC2A1 (0.48) | LMNAKMT2ASLC2A1KCNH2DRD2 | |
| SCHEMBL5772802 | 0.83 | SLC2A1 (0.48) | KMT2ARAB9ASLC2A1KCNH2DRD2 | |
| SCHEMBL5775396 | 0.83 | KCNH2 (0.49) | SLC2A1KCNH2DRD2SIGMAR1DRD3 | |
| SCHEMBL5773815 | 0.81 | SLC2A1 (0.45) | KMT2ASLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5778699 | 0.80 | SLC2A1 (0.58) | LMNAKMT2ASLC2A1KCNH2DRD2 | |
| SCHEMBL5777778 | 0.80 | SLC2A1 (0.47) | LMNAKMT2ASLC2A1KCNH2DRD2 | |
| SCHEMBL5774216 | 0.79 | SLC2A1 (0.49) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5773156 | 0.78 | SLC2A1 (0.57) | LMNAKMT2ASLC2A1KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |