Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773206 | 0.74 | STAT3 (0.42) | GSK3BTOP2ATOP2B | |
| SCHEMBL29023850 | 0.72 | KDM4E (0.41) | GSK3BPIM1GSK3APRKD3IRAK1 | |
| SCHEMBL139670 | 0.70 | KCNH2 (0.35) | GSK3BPIM1GSK3APRKD3PIM3 | |
| SCHEMBL141441 | 0.69 | KCNH2 (0.31) | KCNH2DRD2DRD1DRD4DRD5 | |
| SCHEMBL10413065 | 0.67 | ALDH1A1 (0.46) | GSK3BTOP2ATOP2B | |
| SCHEMBL4296349 | 0.67 | ADRB2 (0.47) | KCNH2TOP2ATOP2B | |
| SCHEMBL9014024 | 0.66 | PRKD3 (0.40) | GSK3BPIM1GSK3APRKD3IRAK1 | |
| SCHEMBL28440264 | 0.62 | PIM1 (0.38) | GSK3BPIM1GSK3APRKD3IRAK1 | |
| SCHEMBL10412669 | 0.62 | ALDH1A1 (0.48) | DRD3TP53 | |
| SCHEMBL7119688 | 0.61 | HPGD (0.57) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349853-B1 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | PHARMACIA & UPJOHN CO LLC (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6869965-B2 | Such as 2-methylpropyl-(4-bromo-3-fluorophenyl)carbamate | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-22 | — | — | US | disclosed |
| US-20040215017-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | PHARMACIA & UPJOHN COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-6689769-B2 | BACTERICIDES | PHARMACIA & UPJOHN COMPANY | 2004-02-10 | — | — | US | disclosed |
| US-20030013737-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | PHARMACIA & UPJOHN COMPANY | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013737-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | BRD7, BRD1, NQO2 | GSK3B 2572/4885PIM1 3560/4885GSK3A 2099/4885 |
| US-20040215017-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | BRD7, BRD1, NQO2 | GSK3B 2572/4885PIM1 3560/4885GSK3A 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.