Isophthalic Acid

Isophthalic Acid

SCHEMBL5773756

O=C(O)c1ccc2ccccc2c1C(=O)O.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.54
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 2/20 0.53
HPGD P15428 2/20 0.53
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
CYP1A2 P05177 1/20 0.53
GLA P06280 1/20 0.53
CYP2C19 P33261 1/20 0.53
LDHA P00338 1/20 0.53
CDC25B P30305 1/20 0.51
PTPN1 P18031 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
PLA2G2D Q9UNK4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11239275 0.93 WDR5 (0.58) WDR5KMT2AMEN1ALDH1A1HSD17B10
Benzoic Acid SCHEMBL4963616 0.92 WDR5 (0.59) WDR5KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL7024975 0.90 WDR5 (0.54) WDR5KMT2AMEN1ALDH1A1HSD17B10
Terephthalic Acid SCHEMBL422894 0.88 WDR5 (0.59) WDR5KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL27804512 0.88 WDR5 (0.68) WDR5KMT2AMEN1ALDH1A1HSD17B10
Benzene SCHEMBL27549874 0.88 WDR5 (0.68) WDR5KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL33850 0.88 WDR5 (0.68) WDR5KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL29376013 0.88 WDR5 (0.68) WDR5KMT2AMEN1ALDH1A1HSD17B10
SCHEMBL4577224 0.86 WDR5 (0.66) WDR5KMT2AMEN1ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL608188 0.86 LDHA (0.69) WDR5KMT2AMEN1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1263844-B1 EXTRUSION PROCESS FOR DISPERSION PRODUCTION ICI PLC (GB) 2006-09-13 EP disclosed
EP-1162229-B1 Coated polyester film TOYO BOSEKI (JP) 2005-02-23 EP disclosed
EP-1263844-A2 EXTRUSION PROCESS FOR DISPERSION PRODUCTION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2002-12-11 EP disclosed
WO-2001064774-A2 EXTRUSION PROCESS FOR DISPERSION PRODUCTION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2001-09-07 WO disclosed
EP-0456929-A2 A semitransparent resin container having pearl gray glossiness SHISEIDO COMPANY LIMITED (JP) 1991-11-21 EP disclosed
EP-0251711-A2 Thermoplastic polyester resin composition POLYPLASTICS CO. LTD. (JP) 1988-01-07 EP disclosed
EP-0251712-A2 Thermoplastics polyester resin composition POLYPLASTICS CO. LTD. (JP) 1988-01-07 EP disclosed