Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775005 | 0.89 | NPY5R (0.47) | NPY5RKDM4EALDH1A1MAPK1PRKCI | |
| Hydrochloric Acid SCHEMBL5774152 | 0.87 | NPY5R (0.46) | NPY5RKDM4EALDH1A1MAPK1PRKCI | |
| SCHEMBL5771955 | 0.77 | MEN1 (0.51) | NPY5RKDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5776500 | 0.76 | MEN1 (0.50) | NPY5RKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5773316 | 0.76 | NPY5R (1.00) | NPY5RKDM4EALDH1A1MAPK1PRKCI | |
| Hydrochloric Acid SCHEMBL5774363 | 0.75 | NPY5R (0.97) | NPY5RKDM4EALDH1A1MAPK1PRKCI | |
| SCHEMBL5778378 | 0.74 | NPY5R (0.62) | NPY5R | |
| SCHEMBL5772205 | 0.68 | NPY5R (0.69) | NPY5RKDM4EALDH1A1MAPK1GAA | |
| Hydrochloric Acid SCHEMBL5774401 | 0.67 | NPY5R (0.67) | NPY5RKDM4EALDH1A1MAPK1GAA | |
| SCHEMBL5772334 | 0.64 | NPY5R (0.78) | NPY5RPRKCIMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |