Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5774152 | 0.98 | NPY5R (0.46) | NPY5RMCHR1KDM4EMAPTHPGD | |
| SCHEMBL5773830 | 0.89 | NPY5R (0.61) | NPY5RKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL5771155 | 0.77 | NPY5R (0.78) | NPY5RMCHR1KDM4EMAPTHPGD | |
| Hydrochloric Acid SCHEMBL5773817 | 0.76 | NPY5R (0.76) | NPY5RMCHR1KDM4EMAPTHPGD | |
| SCHEMBL5771955 | 0.75 | MEN1 (0.51) | NPY5RKDM4EMAPTNPSR1NPC1 | |
| Hydrochloric Acid SCHEMBL5776500 | 0.74 | MEN1 (0.50) | NPY5RKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL5772334 | 0.65 | NPY5R (0.78) | NPY5RSMN1; SMN2PRKCI | |
| SCHEMBL5773316 | 0.65 | NPY5R (1.00) | NPY5RKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL5778378 | 0.64 | NPY5R (0.62) | NPY5R | |
| Hydrochloric Acid SCHEMBL5773169 | 0.64 | NPY5R (0.74) | NPY5RSMN1; SMN2PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |