SCHEMBL577391

SCHEMBL577391

ON=C1c2ccccc2-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 1.00
MEN1 O00255 5/20 1.00
CDK5 Q00535 4/20 0.67
CDK5R1 Q15078 4/20 0.67
MAPT P10636 4/20 0.53
NCOA1 Q15788 3/20 0.53
NCOA3 Q9Y6Q9 3/20 0.53
HSP90AA1 P07900 2/20 0.53
ALDH1A1 P00352 4/20 0.50
AURKA O14965 4/20 0.48
KDR P35968 4/20 0.48
AURKB Q96GD4 4/20 0.48
MAPK10 P53779 2/20 0.46
PTK2B Q14289 2/20 0.46
TSHR P16473 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GAA P10253 1/20 0.43
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941712 1.00 KMT2A (1.00) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL3401938 0.97 KMT2A (0.94) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL29493736 0.97 KMT2A (0.94) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL17546590 0.94 KMT2A (0.88) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL17503329 0.94 KMT2A (0.88) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL31286023 0.94 KMT2A (0.88) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL17988338 0.84 MEN1 (0.71) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL10624320 0.82 MEN1 (0.68) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL17988342 0.82 MEN1 (0.68) KMT2AMEN1CDK5CDK5R1MAPT
SCHEMBL3956832 0.82 MEN1 (0.68) KMT2AMEN1CDK5CDK5R1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111675591-B Synthetic method of benzophenanthrene compound 安徽师范大学 2022-09-30 CN claimed
CN-111675591-A Synthetic method of benzophenanthrene compound 安徽师范大学 2020-09-18 CN claimed
CN-103751943-A Fire extinguishing composition containing nitrogenous organic compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-30 CN claimed
US-20070114155-A1 Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof TOTAL RAFFINAGE FRANCE (FR) 2007-05-24 US claimed
JP-2007501701-A 2007-02-01 JP claimed
EP-1660232-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF Total France (FR) 2006-05-31 EP claimed
WO-2005016518-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF TOTAL FRANCE (FR) 2005-02-24 WO claimed
WO-2003099757-A1 STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-12-04 WO claimed
US-6525043-B2 Bicyclic or tricyclic ketones, oximes, amine oxides or amines are used as calcium or potassium channel modulators NEUROSEARCH A/S (DK) 2003-02-25 US claimed
US-20020065266-A1 Use of ion channel modulating agents NEUROSEARCH A/S (DK) 2002-05-30 US claimed
EP-1187610-A2 USE OF ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2002-03-20 EP claimed
EP-0661357-B1 Polymeric pigment dispersants for use in coating compositions BASF CORP (US) 2001-10-31 EP claimed
WO-2000069794-A2 USE OF CALCIUM-ACTIVATED POTASSIUM CHANNEL-MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-11-23 WO claimed
EP-0661357-A2 Polymeric pigment dispersants for use in coating compositions BASF CORPORATION (US) 1995-07-05 EP claimed
US-5378762-A Functionalized acrylic copolymer with polyether and modified with hydrazide, hydrazone or oxime BASF CORPORATION (US) 1995-01-03 US claimed
US-20250109095-A1 METHOD FOR PREPARING OXIME DERIVATIVE SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-04-03 US disclosed
US-20240368001-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-11-07 US disclosed
US-4169897-A VIRICIDES RICHARDSON-MERRELL INC. (US) 1979-10-02 US disclosed
US-4059702-A ANTIVIRAL RICHARDSON-MERRELL INC. (US) 1977-11-22 US disclosed
US-3932643-A INTERFERON INDUCERS PFIZER INC. (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065266-A1 Use of ion channel modulating agents KCNN3, KCNN1, KCNN2 KMT2A 2397/4885MEN1 3455/4885CDK5 1207/4885
US-20250109095-A1 METHOD FOR PREPARING OXIME DERIVATIVE NOS2, NOS1, NOS3 KMT2A 2283/4885MEN1 2784/4885CDK5 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.