Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 12/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772116 | 0.91 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1HTR1AADRA1D | |
| SCHEMBL5773885 | 0.84 | KCNH2 (0.68) | SLC2A1KCNH2 | |
| SCHEMBL5775396 | 0.81 | KCNH2 (0.49) | SLC2A1KCNH2SIGMAR1HTR1A | |
| SCHEMBL5772791 | 0.80 | KCNH2 (0.37) | KCNH2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5255719 | 0.80 | SLC2A1 (0.43) | SLC2A1KCNH2 | |
| SCHEMBL5776996 | 0.79 | SLC2A1 (0.54) | SLC2A1KCNH2HTR1A | |
| SCHEMBL5253483 | 0.79 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5778699 | 0.79 | SLC2A1 (0.58) | SLC2A1KCNH2SIGMAR1HTR1AADRA1D | |
| SCHEMBL5773156 | 0.79 | SLC2A1 (0.57) | SLC2A1KCNH2SIGMAR1HTR1AADRA1D | |
| SCHEMBL5777778 | 0.79 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |