Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690604 | 0.88 | SLC2A1 (0.36) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL4275508 | 0.84 | KCNH2 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL5778069 | 0.84 | MEN1 (0.38) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL5778699 | 0.83 | SLC2A1 (0.58) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL5775396 | 0.83 | KCNH2 (0.49) | SLC2A1KCNH2HTR1ADRD2SIGMAR1 | |
| SCHEMBL5772116 | 0.83 | SLC2A1 (0.48) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL5775617 | 0.81 | SLC2A1 (0.44) | SLC2A1KCNH2HTR1ASIGMAR1MEN1 | |
| SCHEMBL5773156 | 0.81 | SLC2A1 (0.57) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL3781930 | 0.81 | SLC2A1 (0.52) | SLC2A1KCNH2HTR1ADRD2HTR2B | |
| SCHEMBL3698321 | 0.80 | HCRTR1 (0.35) | KCNH2HTR1ADRD2HTR2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |