Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LITAF | Q99732 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774216 | 0.80 | SLC2A1 (0.49) | KCNH2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4270110 | 0.77 | KCNH2 (0.49) | KCNH2MC4RTACR1 | |
| SCHEMBL5772116 | 0.70 | SLC2A1 (0.48) | KCNH2ADORA2AKDM4EALDH1A1HTR1A | |
| SCHEMBL4721450 | 0.67 | CCR8 (0.53) | KCNH2ADORA2AHTR1AADRA1DADRA1A | |
| SCHEMBL5773885 | 0.67 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL3686475 | 0.65 | KCNH2 (0.40) | KCNH2KDM4EALDH1A1TACR1HTR1A | |
| SCHEMBL13857010 | 0.63 | FAAH (0.41) | KDM4EALDH1A1 | |
| SCHEMBL3689424 | 0.63 | HTR1A (0.44) | KCNH2KDM4EALDH1A1TACR1HTR1A | |
| SCHEMBL4718696 | 0.63 | CCR8 (0.53) | KCNH2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL23360169 | 0.62 | HTR1A (0.49) | ALDH1A1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |