Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873335 | 0.76 | CMA1 (0.38) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL3870014 | 0.69 | FAAH (0.40) | DAGLAFAAHCES1XDH | |
| SCHEMBL3873491 | 0.69 | XDH (0.39) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL4050534 | 0.67 | DAGLA (0.55) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL5800404 | 0.67 | CTSS (0.43) | DAGLAFAAHCES1 | |
| SCHEMBL3955586 | 0.65 | DAGLA (0.60) | DAGLAFAAHCES1XDH | |
| SCHEMBL28171663 | 0.65 | DAGLA (0.66) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL4047648 | 0.65 | FAAH (0.44) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL4049877 | 0.64 | DAGLA (0.62) | DAGLAFAAHCES1XDH | |
| SCHEMBL5773459 | 0.63 | DAGLA (0.43) | DAGLAFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682524-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2005040142-A9 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMA INC (US) | 2005-06-09 | — | — | WO | claimed |
| WO-2005040142-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-06 | — | — | WO | claimed |
| EP-1682524-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005040142-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-06 | — | — | WO | disclosed |