Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573782 | 0.84 | GRIN2D (0.43) | ALOX15MEN1CYP1A2BLMKMT2A | |
| SCHEMBL9573817 | 0.81 | CA12 (0.38) | ALOX15MEN1CYP1A2BLMKMT2A | |
| SCHEMBL5777941 | 0.80 | POLB (0.40) | ALOX15MEN1CYP1A2KMT2AGRIN2D | |
| SCHEMBL5397544 | 0.80 | ALOX15 (0.66) | ALOX15CYP1A2HPGDCYP2C19 | |
| SCHEMBL5812465 | 0.78 | ALOX15 (0.54) | ALOX15MEN1CYP1A2KMT2AHPGD | |
| SCHEMBL7255962 | 0.77 | MEN1 (0.42) | ALOX15MEN1CYP1A2BLMKMT2A | |
| SCHEMBL4337035 | 0.76 | GRIN1 (0.48) | ALOX15MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL5776615 | 0.74 | KDM4E (0.45) | ALOX15MEN1KMT2AHPGDTSHR | |
| SCHEMBL4344101 | 0.74 | GRIN1 (0.39) | MEN1CYP1A2BLMKMT2AHPGD | |
| SCHEMBL5775281 | 0.72 | KDM4E (0.48) | ALOX15MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472221-B1 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | GRUENENTHAL GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1472221-A2 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | Grünenthal GmbH (DE) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003037863-A2 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | disclosed |
| WO-1994013637-A1 | HYDROXYIMINOALKYLINDOLE CARBOXYLIC ACID DERIVATIVES USED AS ANTAGONISTS OF EXCITATORY AMINO ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1994-06-23 | — | — | WO | disclosed |