Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.80 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.71 |
| ▸ | SCD | O00767 | 1/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688998 | 0.93 | MEN1 (0.87) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10962764 | 0.83 | KMT2A (0.74) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL1270375 | 0.83 | SCD (0.89) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL27771294 | 0.82 | KMT2A (0.77) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10808167 | 0.82 | BAZ1A (0.79) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10922701 | 0.82 | KMT2A (0.72) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL7128794 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL5778644 | 0.81 | SCD (0.69) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2754070 | 0.81 | ADORA3 (0.74) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2754003 | 0.81 | SCD (0.69) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |