Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772229 | 0.88 | SIGMAR1 (0.52) | HTR7HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL5776696 | 0.87 | SIGMAR1 (0.51) | HTR7HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL5776645 | 0.86 | KCNH2 (0.57) | HTR7HTR1ASLC6A3DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5770744 | 0.84 | SIGMAR1 (0.51) | HTR7HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL5776276 | 0.84 | SIGMAR1 (0.58) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL5773754 | 0.84 | ADRA1B (0.49) | HTR1ADRD3 | |
| SCHEMBL5775439 | 0.83 | MAPT (0.45) | HTR7DRD2SLC6A2SLC6A3DRD4 | |
| SCHEMBL5774541 | 0.83 | HTR1A (0.49) | HTR1ADRD2HTR2ADRD4DRD3 | |
| SCHEMBL5772832 | 0.83 | SIGMAR1 (0.53) | HTR7HTR1ADRD2HTR2ADRD4 | |
| Hydrochloric Acid SCHEMBL5772589 | 0.82 | HTR1A (0.48) | HTR1ADRD2HTR2ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-B1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |