Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.81 | GAA (0.43) | ALDH1A1HPGDTHRBMAPTTP53 | |
| SCHEMBL7997945 | 0.80 | SMN1; SMN2 (0.36) | ALDH1A1CSNK1DMAPTNPC1RAB9A | |
| SCHEMBL7997967 | 0.79 | KDM4E (0.41) | ALDH1A1CSNK1DMAPTNPC1RAB9A | |
| SCHEMBL5775077 | 0.79 | KDM4E (0.37) | ALDH1A1HPGDTHRBCSNK1DMAPT | |
| SCHEMBL6790398 | 0.78 | GAA (0.50) | MAPTTP53 | |
| SCHEMBL7998415 | 0.77 | KDM4E (0.39) | ALDH1A1CSNK1DMAPTNPC1RAB9A | |
| SCHEMBL7993931 | 0.76 | GAA (0.41) | ALDH1A1HPGDTHRBMAPTTP53 | |
| SCHEMBL8001808 | 0.76 | GAA (0.42) | THRBMAPTTP53 | |
| SCHEMBL7983540 | 0.75 | GAA (0.40) | ALDH1A1HPGDMAPTTP53SMN1; SMN2 | |
| SCHEMBL7997959 | 0.75 | KDR (0.43) | ALDH1A1HPGDTHRBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055142-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |