Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997967 | 0.83 | KDM4E (0.41) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL7998327 | 0.81 | MAPK14 (0.32) | — | |
| SCHEMBL7978072 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2LMNAALDH1A1CSNK1DRAB9A | |
| SCHEMBL5735113 | 0.80 | GAA (0.43) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7998415 | 0.80 | KDM4E (0.39) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL7984009 | 0.79 | CACNA1H (0.38) | MAPK10CSNK1DCCNE1CDK2CDK5 | |
| SCHEMBL5775077 | 0.78 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1CSNK1DMAPT | |
| SCHEMBL6790398 | 0.77 | GAA (0.50) | KDM4EGAAMAPT | |
| SCHEMBL7984012 | 0.77 | TRPV1 (0.37) | KDM4EALDH1A1GAAMAPK10CSNK1D | |
| SCHEMBL7994588 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |