Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776715 | 0.79 | PDE3B (0.35) | CYP1A2 | |
| SCHEMBL16429508 | 0.74 | TAAR1 (0.49) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL5779423 | 0.74 | CYP1A2 (0.40) | NPC1RAB9ACYP1A2KDM4ESLC6A4 | |
| SCHEMBL9302323 | 0.73 | NPC1 (0.41) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL27976769 | 0.72 | ALDH1A1 (0.50) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL3525605 | 0.71 | NPC1 (0.49) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL29733200 | 0.70 | MEN1 (0.57) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL21000902 | 0.70 | MEN1 (0.57) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL29390450 | 0.70 | NPC1 (0.52) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL902873 | 0.70 | NPC1 (0.52) | CYP3A4ALDH1A1NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |