Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776458 | 0.79 | CYP3A4 (0.41) | CYP1A2 | |
| SCHEMBL4155227 | 0.64 | SLC18A3 (0.42) | CYP1A2 | |
| SCHEMBL239860 | 0.63 | CYP1A2 (0.46) | PDE3BPDE3ACYP1A2GUSB | |
| SCHEMBL29746469 | 0.63 | CYP1A2 (0.46) | PDE3BPDE3ACYP1A2GUSB | |
| SCHEMBL5779423 | 0.63 | CYP1A2 (0.40) | CYP1A2 | |
| SCHEMBL5779681 | 0.62 | IRAK4 (0.36) | — | |
| SCHEMBL8889348 | 0.61 | MEN1 (0.50) | CYP1A2 | |
| SCHEMBL3071480 | 0.60 | BACE1 (0.60) | CYP1A2 | |
| SCHEMBL29980068 | 0.60 | CYP1A2 (0.42) | PDE3BPDE3ACYP1A2GUSB | |
| SCHEMBL2757268 | 0.60 | ALDH1A1 (0.51) | PDE3BPDE3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |