Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 8/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739938 | 0.91 | MAPT (0.42) | POLB | |
| SCHEMBL6399135 | 0.84 | — | — | |
| SCHEMBL5738728 | 0.81 | MEN1 (0.39) | HTR1A | |
| SCHEMBL5779711 | 0.79 | HTR1A (0.39) | HTR1A | |
| SCHEMBL6398289 | 0.78 | DRD2 (0.52) | HTR1A | |
| SCHEMBL5737988 | 0.77 | HTR1A (0.30) | HTR1A | |
| SCHEMBL6399094 | 0.74 | — | — | |
| SCHEMBL5778809 | 0.71 | KDR (0.43) | — | |
| SCHEMBL6399312 | 0.69 | DRD2 (0.46) | HTR1A | |
| SCHEMBL5738181 | 0.67 | HTR1A (0.44) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697334-A1 | HETEROCYCLIC SUBSTITUTED INDANE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | Warner-Lambert Company LLC (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005056540-A1 | HETEROCYCLIC SUBSTITUTED INDANE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |