Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997290 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTALOX15HSD17B10CYP1A2 | |
| SCHEMBL7381366 | 0.73 | HTR6 (0.74) | ALDH1A1MAPTNPSR1HTR6DRD2 | |
| SCHEMBL5746891 | 0.72 | KMT2A (0.52) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL488403 | 0.72 | KDM4E (0.61) | ALDH1A1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL5472147 | 0.70 | KDM4E (0.55) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL1345949 | 0.70 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL1346088 | 0.69 | KMT2A (0.51) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL1343970 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL1344093 | 0.69 | ALDH1A1 (0.58) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8938451 | 0.69 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |