Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090931 | 0.82 | KMT2A (0.58) | KMT2AMAPK8PLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL6090219 | 0.79 | KMT2A (0.54) | KMT2AMAPK8PLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL5776548 | 0.72 | ALDH1A1 (0.48) | KMT2ALIPGMAPTLPLSMN1; SMN2 | |
| SCHEMBL11263827 | 0.70 | KMT2A (0.60) | KMT2APLA2G2ASMN1; SMN2 | |
| SCHEMBL4886339 | 0.70 | PLA2G2A (0.55) | KMT2AMAPK8PLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL11729659 | 0.69 | KMT2A (0.56) | KMT2AMAPK8MAPTSMN1; SMN2TSHR | |
| SCHEMBL4893680 | 0.69 | AR (0.60) | KMT2APLA2G2AMAPTSMN1; SMN2AR | |
| SCHEMBL2799600 | 0.68 | LPL (0.56) | LIPGPLA2G2ALPL | |
| SCHEMBL17206150 | 0.68 | MAPT (0.45) | KMT2ALIPGMAPTLPLSMN1; SMN2 | |
| SCHEMBL5739485 | 0.68 | ACLY (0.53) | KMT2AMAPK8MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |