Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | XBP1 | P17861 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556254 | 0.86 | CYP1A2 (0.55) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL12496609 | 0.85 | ALDH1A1 (0.66) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL7671532 | 0.85 | HTR6 (0.68) | ALDH1A1HPGDMAPTTP53HTR6 | |
| SCHEMBL9189433 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL8938387 | 0.84 | NHERF1 (0.66) | ALDH1A1NHERF1MAPTMEN1KMT2A | |
| SCHEMBL4614808 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL29617493 | 0.82 | ALDH1A1 (0.66) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL21264669 | 0.82 | ALDH1A1 (0.66) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL15622584 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL2715272 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210251958-A1 | Antibacterial Compounds | RHODE ISLAND HOSPITAL, A LIFESPAN-PARTNER | 2021-08-19 | — | — | US | disclosed |
| US-10577356-B2 | Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2020-03-03 | — | — | US | disclosed |
| US-10577356-B2 | Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190040045-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2019-02-07 | — | — | US | disclosed |
| US-20190040045-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2019-02-07 | — | — | US | disclosed |
| US-10118914-B2 | Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170166554-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166554-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166554-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2017-06-15 | — | — | US | disclosed |
| WO-2015195486-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2015-12-23 | — | — | WO | disclosed |
| WO-2015044928-A1 | SUBSTITUTED INDOLES AND THEIR USE AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | STELLENBOSCH UNIVERSITY (ZA) | 2015-04-02 | — | — | WO | disclosed |
| US-5527819-A | TREATING AIDS | MERCK & CO., INC. (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0686148-A4 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0686148-A1 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO. INC. (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0678508-A1 | Indoles as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1995-10-25 | — | — | EP | disclosed |
| WO-1994019321-A1 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| WO-1993005020-A1 | INDOLES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1993-03-18 | — | — | WO | disclosed |
| EP-0530907-A1 | Indoles as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166554-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | CNR1, CNR2, ARRB1 | ALDH1A1 2372/4885CYP1A2 2107/4885HPGD 2094/4885 |
| US-10577356-B2 | Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them | CNR1, CNR2, ARRB1 | ALDH1A1 2372/4885CYP1A2 2107/4885HPGD 2094/4885 |
| US-10118914-B2 | Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them | CNR1, CNR2, ARRB1 | ALDH1A1 2372/4885CYP1A2 2107/4885HPGD 2094/4885 |
| US-11690824-B2 | Antibacterial compounds | MRPL21, SPOUT1, BAX | ALDH1A1 2131/4885CYP1A2 2853/4885HPGD 502/4885 |
| US-20210251958-A1 | Antibacterial Compounds | MRPL21, SPOUT1, BAX | ALDH1A1 2131/4885CYP1A2 2853/4885HPGD 502/4885 |
| US-20190040045-A1 | BETA-ARRESTIN-BIASED CANNABINOID CB1 RECEPTOR AGONISTS AND METHODS FOR MAKING AND USING THEM | CNR1, CNR2, ARRB1 | ALDH1A1 2372/4885CYP1A2 2107/4885HPGD 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.