SCHEMBL775690

SCHEMBL775690

C1=C2CCC2c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.35
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
ADRA1A P35348 1/20 0.32
IDO1 P14902 1/20 0.31
PDPK1 O15530 1/20 0.31
PDGFRA P16234 1/20 0.30
PRKACA P17612 1/20 0.30
KDR P35968 1/20 0.30
CDK8 P49336 1/20 0.30
CDK9 P50750 1/20 0.30
ROCK1 Q13464 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3248949 1.00 KDM1A (0.35) KDM1ADDB1CRBNADRA1AIDO1
SCHEMBL6561593 0.98 KDM1A (0.34) KDM1ADDB1CRBNADRA1A
SCHEMBL577658 0.91 KDM1A (0.39) KDM1AIDO1PDPK1
SCHEMBL5845510 0.88 TLR4 (0.35) KDM1AADRA1AIDO1
SCHEMBL5844300 0.86 TLR4 (0.42) KDM1AADRA1A
SCHEMBL5846236 0.84 TLR4 (0.41) KDM1AADRA1A
SCHEMBL7696567 0.83 KDM1A (0.32) KDM1A
SCHEMBL1664601 0.79 ADRA2A (0.40)
SCHEMBL29608131 0.77 GRIN2D (0.38) KDM1A
SCHEMBL6560462 0.76 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120071605-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS AND NON-FUNCTIONALIZED PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2012-03-22 US claimed
WO-2009096921-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS AND NON-FUNCTIONALIZIED PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-08-06 WO claimed
US-20240092007-A1 Thermoplastic Vulcanizate Compositions including Cyclic Olefin Copolymers CELANESE INT CORP (US) 2024-03-21 US disclosed
EP-4291608-A1 THERMOPLASTIC VULCANIZATE COMPOSITIONS INCLUDING CYCLIC OLEFIN COPOLYMERS Celanese International Corporation (US) 2023-12-20 EP disclosed
CN-116917405-A Thermoplastic vulcanizate compositions comprising cycloolefin copolymers 国际人造丝公司 2023-10-20 CN disclosed
US-9186772-B2 Chemical mechanical polishing pad with broad spectrum, endpoint detection window and method of polishing therewith ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2015-11-17 US disclosed
US-20140256225-A1 Chemical Mechanical Polishing Pad With Broad Spectrum, Endpoint Detection Window and Method of Polishing Therewith DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-11 US disclosed
US-20140256231-A1 Multilayer Chemical Mechanical Polishing Pad With Broad Spectrum, Endpoint Detection Window DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-11 US disclosed
US-8344070-B2 Polymer compositions comprising cyclic olefin polymers, polyolefin modifiers, and fillers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-01-01 US disclosed
US-8148472-B1 Polymer compositions comprising cyclic olefin polymers, polyolefin modifiers and non-functionalized plasticizers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-04-03 US disclosed
US-20120071605-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS AND NON-FUNCTIONALIZED PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2012-03-22 US disclosed
US-20090318597-A1 Polymer compositions comprising cyclic olefin polymers, polyolefin modifiers, and fillers EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US disclosed
WO-2009096921-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS AND NON-FUNCTIONALIZIED PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-08-06 WO disclosed
EP-2052022-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN COPOLYMERS AND POLYOLEFIN MODIFIERS ExxonMobil Chemical Patents Inc. (US) 2009-04-29 EP disclosed
EP-2052023-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS, AND FILLERS ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2009-04-29 EP disclosed
WO-2008018951-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS, AND FILLERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-02-14 WO disclosed
WO-2008018952-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN COPOLYMERS AND POLYOLEFIN MODIFIERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-02-14 WO disclosed
US-20080033112-A1 Polymer compositions comprising cyclic olefin copolymers and polyolefin modifiers EXXONMOBIL CHEMICAL PATENTS INC. 2008-02-07 US disclosed