SCHEMBL6561593

SCHEMBL6561593

C1=C2CCC3C(=Cc4ccccc43)CCC2c2ccccc21.[LiH].[LiH]

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.34
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775690 0.98 KDM1A (0.35) KDM1ADDB1CRBNADRA1A
SCHEMBL3248949 0.98 KDM1A (0.35) KDM1ADDB1CRBNADRA1A
SCHEMBL577658 0.89 KDM1A (0.39) KDM1A
SCHEMBL5845510 0.86 TLR4 (0.35) KDM1AADRA1A
SCHEMBL5844300 0.84 TLR4 (0.42) KDM1AADRA1A
SCHEMBL5846236 0.82 TLR4 (0.41) KDM1AADRA1A
SCHEMBL7696567 0.81 KDM1A (0.32) KDM1A
SCHEMBL1664601 0.77 ADRA2A (0.40)
SCHEMBL29608131 0.76 GRIN2D (0.38) KDM1A
SCHEMBL6560462 0.75 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0818458-B1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN CO (JP) 2004-02-25 EP disclosed
US-6339135-B1 AS POLYMERIZATION CATALYST IDEMITSU KOSAN CO., LTD. (JP) 2002-01-15 US disclosed
EP-0818458-A1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-01-14 EP disclosed