SCHEMBL577662

SCHEMBL577662

CC(C)(C)c1cc(-c2cccc3c2Cc2ccccc2-3)ccc1OCCO

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.43
RARG P13631 10/20 0.40
RARA P10276 9/20 0.40
RARB P10826 9/20 0.40
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SLC6A9 P48067 1/20 0.37
PNMT P11086 1/20 0.35
KCNH2 Q12809 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL28408646 0.99 AR (0.42) ARRARGRARARARBKDM4E
SCHEMBL28404201 0.86 AR (0.41) ARRARGRARARARBKDM4E
SCHEMBL28525858 0.85 USP2 (0.36) KDM4EALDH1A1SLC6A9PNMTNPC1
SCHEMBL577075 0.85 AR (0.35) ARRARGRARARARBKDM4E
SCHEMBL577513 0.84 TLR8 (0.39) ARSLC6A9PNMTKCNH2TMEM97
SCHEMBL28980774 0.83 IDO1 (0.41) ARKDM4EALDH1A1SLC6A9PNMT
SCHEMBL577450 0.83 SLC6A9 (0.45) ARKDM4EALDH1A1SLC6A9PNMT
SCHEMBL576515 0.82 RARA (0.40) ARRARGRARARARBKDM4E
SCHEMBL29099228 0.82 ALDH1A1 (0.36) ARKDM4EALDH1A1PNMTKCNH2
SCHEMBL576757 0.81 KCNH2 (0.38) ARKDM4EALDH1A1SLC6A9PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262178-A Polycarbonate resin composition, molded article, and laminate 三菱化学株式会社 2021-01-22 CN disclosed
WO-2020196343-A1 METHODS FOR PRODUCING POLYCARBONATE COPOLYMER AND POLYSILOXANE COMPOUND, POLYCARBONATE COPOLYMER, POLYSILOXANE COMPOUND, COMPOSITION AND MOLDED BODY 三菱瓦斯化学株式会社 2020-10-01 WO disclosed
CN-107849344-B Polycarbonate resin compound 华东理工大学 2020-07-10 CN disclosed
CN-106489085-B Phase difference film, circularly polarizing plate, and image display device 日东电工株式会社 2020-06-30 CN disclosed
CN-107709459-B Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2020-06-19 CN disclosed
CN-107922720-B Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2020-06-19 CN disclosed
CN-107709458-B Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2020-06-19 CN disclosed
CN-111171545-A Polycarbonate resin composition, method for producing same, and molded article 三菱化学株式会社 2020-05-19 CN disclosed
CN-107849345-B Polycarbonate resin composition, method for producing same, and molded article 三菱化学株式会社 2020-03-13 CN disclosed
CN-106471401-B Phase difference film, circularly polarizing plate, and image display device 日东电工株式会社 2020-01-21 CN disclosed
US-8895663-B2 Polycarbonate resin composition and molded article thereof MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-25 US disclosed
US-20140031494-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2014-01-30 US disclosed
CN-102712174-A Resin sheet-coated metal laminate and method for producing same MITSUBISHI CHEM CORP 2012-10-03 CN disclosed
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed
EP-2180014-B1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL CO (JP) 2011-12-14 EP disclosed
US-8058384-B2 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-11-15 US disclosed
US-20100144995-A1 METHOD FOR PRODUCING THERMOPLASTIC RESIN, POLYESTER RESIN AND POLYCARBONATE RESIN, AND THEIR APPLICATIONS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-06-10 US disclosed
EP-2180014-A1 Method for producing thermoplastic resin, polyester resin and polycarbonate resin, and their applications MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-04-28 EP disclosed